5 research outputs found
Fluctuations of cell geometry and their non-equilibrium thermodynamics in living epithelial tissue
We introduce a measure of the entropy production in a living functional
epithelial tissue. We do this by extracting the functional dynamics of
development while at the same time quantifying fluctuations. Using the
translucent Drosophila melanogaster pupal epithelium as an ideal tissue for
high resolution live imaging, we find surprisingly, irreversible dynamics
without entropy production. This is done using a detailed analysis of the
dynamics of the shape and orientation of individual cells which enables
separation of local and global aspects of the tissue behaviour