5 research outputs found

    Fluctuations of cell geometry and their non-equilibrium thermodynamics in living epithelial tissue

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    We introduce a measure of the entropy production in a living functional epithelial tissue. We do this by extracting the functional dynamics of development while at the same time quantifying fluctuations. Using the translucent Drosophila melanogaster pupal epithelium as an ideal tissue for high resolution live imaging, we find surprisingly, irreversible dynamics without entropy production. This is done using a detailed analysis of the dynamics of the shape and orientation of individual cells which enables separation of local and global aspects of the tissue behaviour
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